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2020年 業績

<論文>

  1. Multi-regional sequencing reveals clonal and polyclonal seeding from primary tumor to metastases in advanced gastric cancer.
    Hirotsu Y, Hada M, Amemiya K, Oyama T, Mochizuki H, Omata M.
    J Gastroenterol. 2020;55(5):553-564.
  2. Rapid progressive lung cancers harbouring multiple clonal driver mutations with big bang evolution model.
    Kunimasa K, Hirotsu Y, Nakamura H, Tamiya M, Iijima Y, Ishida H, Hamamoto Y, Maniwa T, Kimura T, Nishino K, Goto T, Amemiya K, Mochizuki H, Oyama T, Nakatsuka SI, Kumagai T, Okami J, Higashiyama M, Imamura F, Omata M.
    Cancer Genet. 2020;241:51-56.
  3. Identification of Clonality through Genomic Profile Analysis in Multiple Lung Cancers.
    Higuchi R, Nakagomi T, Goto T, Hirotsu Y, Shikata D, Yokoyama Y, Otake S, Amemiya K, Oyama T, Mochizuki H, Omata M.
    J Clin Med. 2020;9(2):573.
  4. Dual-molecular barcode sequencing detects rare variants in tumor and cell free DNA in plasma.
    Hirotsu Y, Otake S, Ohyama H, Amemiya K, Higuchi R, Oyama T, Mochizuki H, Goto T, Omata M.
    Sci Rep. 2020;10(1):3391.
  5. Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.
    Kanda T, Goto T, Hirotsu Y, Masuzaki R, Moriyama M, Omata M.
    Int J Mol Sci. 2020;21(4):1525.
  6. Environmental cleaning is effective for the eradication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in contaminated hospital rooms: A patient from the Diamond Princess cruise ship.
    Hirotsu Y, Maejima M, Nakajima M, Mochizuki H, Omata M.
    Infect Control Hosp Epidemiol. 2020:1-2.
  7. Genome analysis of peeling archival cytology samples detects driver mutations in lung cancer.
    Kunimasa K, Hirotsu Y, Amemiya K, Nagakubo Y, Goto T, Miyashita Y, Kakizaki Y, Tsutsui T, Otake S, Kobayashi H, Higuchi R, Inomata K, Kumagai T, Mochizuki H, Nakamura H, Nakatsuka SI, Nishino K, Imamura F, Kumagai T, Oyama T, Omata M.
    Cancer Med. 2020;9(13):4501-4511.
  8. Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide.
    Hirotsu Y, Schmidt-Edelkraut U, Nakagomi H, Sakamoto I, Hartenfeller M, Narang R, Soldatos TG, Kaduthanam S, Wang X, Hettich S, Brock S, Jackson DB, Omata M.
    Int J Mol Sci. 2020;21(11):3895.
  9. Squamous cell carcinoma of the lung with micropapillary pattern.
    Oyama T, Goto T, Amemiya K, Hirotsu Y, Omata M.
    J Thorac Oncol. 2020
  10. Double-quencher probes improve detection sensitivity toward Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a reverse-transcription polymerase chain reaction (RT-PCR) assay.
    Hirotsu Y, Mochizuki H, Omata M.
    J Virol Methods. 2020
  11. Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in Japan.
    Hirotsu Y, Maejima M, Shibusawa M, Amemiya K, Nagakubo Y, Hosaka K, Sueki H, Mochizuki H, Tsutsui T, Kakizaki Y, Miyashita Y, Omata M.
    J Clin Virol. 2020
  12. Primary Driver Mutations in GTF2I Specific to the Development of Thymomas.
    Higuchi R, Goto T, Hirotsu Y, Yokoyama Y, Nakagomi T, Otake S, Amemiya K, Oyama T, Mochizuki H, Omata M.
    Cancers (Basel). 2020;12(8):E2032.
  13. Multiregional sequence revealed SMARCA4 R1192C mutant clones acquired EGFR C797S mutation in the metastatic site of an EGFR-mutated NSCLC patient.
    Kunimasa K, Hirotsu Y, Miyashita Y, Goto T, Amemiya K, Mochizuki H, Samamoto I, Ohki T, Oyama T, Honma K, Imamura F, Nishino K, Kumagai T, Omata M.
    Lung Cancer. 2020;148:28-32.
  14. Comparison of Automated SARS-CoV-2 Antigen Test for COVID-19 Infection with Quantitative RT-PCR using 313 Nasopharyngeal Swabs Including from 7 Serially Followed Patients.
    Hirotsu Y, Maejima M, Shibusawa M, Nagakubo Y, Hosaka K, Amemiya K, Sueki H, Hayakawa M, Mochizuki H, Tsutsui T, Kakizaki Y, Miyashita Y, Yagi S, Kojima S, Omata M.
    Int J Infect Dis. 2020;99:397-402
  15. Comprehensive Analysis of Barrett’s Esophagus: Focused on Carcinogenic Potential for Barrett’s Cancer in Japanese Patients.
    Ishikawa K, Okimoto K, Matsumura T, Hirotsu Y, Amemiya K, Kishimoto T, Akizue N, Ohta Y, Saito K, Maruoka D, Nishimura M, Matsushita K, Mochizuki H, Arai M, Kato J, Yokosuka O, Omata M, Kato N.
    Dig Dis Sci. 2020 in press
  16. Reply to ‘Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in Japan’.
    Hirotsu Y, Maejima M, Shibusawa M, Amemiya K, Nagakubo Y, Hosaka K, Sueki H, Mochizuki H, Tsutsui T, Kakizaki Y, Miyashita Y, Omata M.
    J Clin Virol. 2020;132:104634.
  17. Genomic Profiling Identified ERCC2 E606Q Mutation in Helicase Domain Respond to Platinum-Based Neoadjuvant Therapy in Urothelial Bladder Cancer.
    Hirotsu Y, Yokoyama H, Amemiya K, Hagimoto T, Hosaka K, Oyama T, Mochizuki H, Omata M.
    Front Oncol. 2020;10:1643.
  18. Pooling RT-qPCR testing for SARS-CoV-2 in 1000 individuals of healthy and infection-suspected patients.
    Hirotsu Y, Maejima M, Shibusawa M, Nagakubo Y, Hosaka K, Amemiya K, Sueki H, Hayakawa M, Mochizuki H, Tsutsui T, Kakizaki Y, Miyashita Y, Omata M.
    Sci Rep. 2020;10(1):18899.
  19. Association of Mutation Profiles with Postoperative Survival in Patients with Non-Small Cell Lung Cancer.
    Goto T, Kunimasa K, Hirotsu Y, Nakagomi T, Yokoyama Y, Higuchi R, Otake S, Oyama T, Amemiya K, Mochizuki H, Omata M.
    Cancers (Basel). 2020;12(11):3472.

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